Taking Adalimumab For Rheumatoid Arthritis - 2180 Words

Taking adalimumab for Rheumatoid Arthritis This newsletter is designed to help practising pharmacists understand the application of the basis sciences to practice concerning adalimumab. Lots of practical advice is based on pharmaceutical sciences but once you enter practice it can be hard to remember or find out the basis of why we advise patients in specific ways or why you or other health professionals should handle medicines in certain ways. An effective anti-TNF Adalimumab is an anti-tumour necrosis factor alpha (anti-TNFÃŽ ±) drug used for the treatment of Rheumatic disease, specifically rheumatoid arthritis (Joint Formulary Committee., 2014). Basics of Rheumatoid Arthritis and its treatments. Around 70% of arthritis sufferers in the UK have rheumatoid arthritis (RA). Women are also more likely to develop RA than men, and commonly affects adults between ages 50 and 60. This condition is characterised by an insidious onset of pain, swelling of joints and morning stiffness. Arthritis is caused by inflammation of the synovial tissue of the joints, supposedly triggered by the presence of autobodies such as rheumatoid factors. The first line treatment for RA is a combination of disease modifying anti-rheumatic drug (DMARD). These slow down the progression of RA and treatment typically includes methotrexate in combination with another DMARD (e.g. sulphasalazine). Short term glucocorticoids are also used with DMARDS to manage flares of inflammation. Anti-TNF drugsShow MoreRelatedA Brief Note On The Dormant Form Of Tuberculosis ( Tb )832 Words   |  4 Pages†¢ A huge caution associated with the use of adalimumab is its ability to reactivate, or make one more susceptible to infection. This is because it inhibits TNFÃŽ ± which plays a role in the fighting of infections. Reactivating the dormant form of tuberculosis (TB) is one of the most important infectious adverse reactions in those taking adalimumab. Consequently, patients are assessed for tuberculosis before being offered adalimumab. Other infections include septicaemia and hepatitis B. As a generalRead MoreRheumatoid Arthritis Essay1220 Words   |  5 Pagescriteria for identifying rheumatoid arthritis (RA) earlier in the disease progression was developed by the European League Against Rheumatism (EULAR) and American College of Rheumatology (ACR) in 2010 to allow for earlier intervention and treatment strategies therefore improving outcomes (Aletaha et al., 2010; de Hair et al., 2012; Villeneuve, 2013; Wasserman, 2011). This paper will explore prevention and treatment strategies for Rheumatoid Arthritis (RA). Rheumatoid Arthritis Prevention StrategiesRead MoreCaring For Pregnant Women With Autoimmune Diseases2310 Words   |  10 Pagesceliac disease, irritable bowel disease, type one diabetes, and rheumatoid arthritis. 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Which finding will the nurse expect when assessing a 58-year-old patient who has osteoarthritis (OA) of the knee? a. Discomfort with joint movement b. Heberden’s and Bouchard’s nodes c. Redness and swelling of the knee joint d. Stiffness that increases with movement ANS: A Initial symptoms of OA include pain with joint movement. Heberden’s nodules occur on the fingers. Redness of the joint is moreRead MoreCrohn s Disease And Disease3608 Words   |  15 PagesDisease. most commonly used immunosuppressant drugs are azathioprine (Imuran) and mercaptopurine (Purinethol). Patients taking these drugs must be followed closely by their physicians with frequent blood testing to check for negative side effects. In addition to the aforementioned drugs, methotrexate (Rheumatrex), a drug usually prescribed to treat rheumatoid arthritis, some forms of cancer and psoriasis is sometimes prescribed for people suffering from Crohn’s Disease who do not respond well